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The networking industry is offering new services leveraging recent technological advances in connectivity, storage, and computing such as mobile communications and edge computing. In this regard, extended reality, a term encompassing virtual reality, augmented reality, and mixed reality, can provide unprecedented user experience and pioneering service opportunities such as: live concerts, sports, and other events; interactive gaming and entertainment; immersive education, training, and demos. These services require high-bandwidth, low-latency, and reliable connections, and are supported by next-generation ultra-reliable and low-latency communications in the vision of 6G mobile communication systems. In this work, we devise a novel scheme, called backup from different data centers with multicast and adaptive bandwidth provisioning, to admit reliable, low-latency, and high-bandwidth extended reality live streams in next-generation networks. We consider network services where contents are non-cacheable and investigate how backup services can be offered by different data centers with multicast and adaptive bandwidth provisioning. Our proposed service-provisioning scheme provides protection not only against link failures in the physical network but also against computing and storage failures in data centers. We develop scalable algorithms for the service-provisioning scheme and evaluate their performance on various complex network instances in a dynamic environment. Numerical results show that, compared to conventional service-provisioning schemes such as those seeking backup services from the same data center, our proposed service-provisioning scheme efficiently utilizes network resources, ensures higher reliability, and guarantees low latency; hence, it is highly suitable for extended reality live streams.more » « lessFree, publicly-accessible full text available May 1, 2026
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Torres‐Hernandez, Arnaldo_X; Desman, Prathibha; Nguyen, Thi; Hoang, Vinh; Zhang, Yichao; Bartels, Ashley; Rafferty, Ryan_J (, Chemistry – A European Journal)Abstract Balgacyclamide A−C are a family of cyanobactin natural products isolated from freshwater cyanobacteriaMicrocystis aeruginosa. These macrocyclic peptides are characterized by their oxazoline‐thiazole core, their 7 or 8 stereocenters, and their antiparasitic activities. Balgacyclamide B is known for its activity towardsPlasmodium falciparumchloroquine‐resistant strain K1,Trypanosoma brucei rhodesiense, andLeishmania donovani. In this report, the first total synthesis of Balgacyclamide B is described in a 17‐steps pathway and a 2 % overall yield. The synthetic pathway toward balgacyclamide B can be adapted for the future syntheses of balgacyclamide A and C. In addition, a brief history background of oxazolines syntheses is shown to emphasize the importance of the cyclization conditions used to interconvert or retain configuration of β‐hydroxy amides via dehydrative cyclization.more » « less
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